African Medical Centre of Excellence (AMCE)
Health care + 1 more
Description
Qualifications
- MD/PhD in Genetics, Molecular Biology, Genomics, or a closely related field.
- An MD/PhD or equivalent clinical genetics qualification is highly advantageous.
- Certification or fellowship in Clinical Molecular Genetics, Laboratory Genetics, or a relevant specialty board is preferred.
- Demonstrated experience with NGS technologies, bioinformatics, and genomic data interpretation.
- Minimum of 7 years of progressive experience in a molecular genetics or genomics laboratory, with at least 3 years in a leadership role.
- Proven track record in managing a high-complexity clinical genetics laboratory.
- Strong publication record and success in securing competitive research funding.
- Expertise in genetic variant interpretation, classification, and reporting standards (ACMG/AMP guidelines).
- Experience with laboratory information management systems (LIMS) and bioinformatics tools.
- Excellent leadership, communication, and stakeholder engagement skills.
- Knowledge of ethical, legal, and social implications (ELSI) of genetic testing and data sharing.
Responsibilities
Strategic Leadership & Departmental Management
- Develop and implement the strategic vision for the Molecular Genetics Department in alignment with the hospital’s mission and goals.
- Provide executive leadership to the department, overseeing all operational, clinical, and research activities.
- Manage departmental resources, including budget planning, staffing, and procurement of advanced laboratory equipment and technologies.
- Establish and monitor key performance indicators (KPIs) for quality, turnaround time, and service efficiency.
Clinical Diagnostic Services
- Oversee the delivery of high-complexity molecular genetic testing, including next-generation sequencing (NGS), PCR-based assays, Sanger sequencing, and cytogenetic/molecular cytogenetic analyses.
- Ensure accurate interpretation and reporting of genetic test results, including variant classification and clinical correlation.
- Implement and maintain rigorous quality control, proficiency testing, and validation protocols for all assays.
- Serve as the primary consultant for clinicians regarding test selection, result interpretation, and patient management implications.
Research & Innovation
- Lead and foster a robust research program in molecular genetics and genomics, focusing on translational and clinical research.
- Secure competitive research grants and collaborate with national and international research consortia.
- Drive innovation in genomic technologies, bioinformatics pipelines, and data integration for precision medicine.
- Publish findings in high-impact journals and present at scientific conferences.
Bioinformatics & Data Science Oversight
- Supervise the development, validation, and maintenance of bioinformatics pipelines for genomic data analysis.
- Ensure secure management, storage, and interpretation of large-scale genomic data in compliance with ethical and data protection standards.
- Integrate genomic data with electronic health records (EHR) to support clinical decision-making and personalized treatment plans.
Compliance, Accreditation & Quality Assurance
- Ensure compliance with national (MLSCN, NAFDAC) and international (ISO 15189, CAP, CLIA) accreditation standards.
- Prepare for and lead external audits and inspections.
- Maintain comprehensive documentation for all laboratory processes, validations, and quality management systems.
- Implement and oversee continuous quality improvement initiatives.
Education & Collaboration
- Foster interdisciplinary collaboration with departments such as Oncology, Pediatrics, Neurology, and Pathology.
- Serve as a key representative in hospital committees related to genetics, precision medicine, and ethics.
Team Leadership & Development
- Support to develop a high-performing team of geneticists, laboratory scientists, bioinformaticians, and support staff.
- Promote a culture of scientific excellence, continuous learning, and professional development.
- Manage staff scheduling, performance evaluations, and career progression pathways
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