Aga Khan Hospitals
Health care + 1 more
Description
Requirements
BSc or MSc in Molecular Biology/Biochemistry or relevant field.
Relevant Experience
- At least 3 years of work experience working in a genomic lab or similar field
- Familiar with various molecular techniques such as next-generation sequencing and impeccable attention to detail.
- Working knowledge in basic sciences with skills in laboratory techniques
Personal Characteristics & Behaviours
- Able to work accurately and efficiently, be detail oriented, and work both independently and within a group
- Ability to multitask several projects and work in fast paced environment
- Proven ability to work well with certain degree of autonomy and function successfully in a team environment
- Strong commitment to superior quality professional service
- Good verbal, written and interpersonal communication skills
- Self-motivated and professional
Responsibilities
Sample Processing & Preparation
- Accurate logging, labelling using barcodes, documentation and proper storage of samples in appropriate temperature-controlled freezers
- DNA and RNA isolation from blood samples, human tissues and other biological specimens.
- Quantification and quality control of DNA and RNA using nanodrop and Qubit
Library Preparation & Sequencing
- Library preparation of nucleic acid including fragmentation, adaptor ligation, amplification and sequencing on Illumina NGS platform.
- Monitor sequencing runs and troubleshoot
Quality Control & Assurance
- Secure and transfer data for primary, secondary and tertiary analysis
- Secure and transfer data for primary, secondary and tertiary analysis
- Assist faculty in research - Conduct experiments, analyse data and interpret results
- Assist in write-up, manuscripts, research reports, presentations, research grant applications and abstracts for publication and grant funding
- Responsible for assisting in preparing and assembling all standard operating procedures (SOPs) for NGS Core Facility
- Maintain and enhance bioinformatics pipelines and databases used in variant analysis.
- Implement best practices for data management, version control, and documentation.
- Evaluate new bioinformatics tools and methods to improve analysis accuracy and efficiency.
Laboratory Operations
- Raise PR and MSR for research supplies and consumables, liaise with purchase and AKU Warehouse departments to ensure timely delivery of the requested items and keep track records.
- Lodge complaints about breakdown of capital equipment used for lab research and follow-up with relevant department
- Engage in professional development activities such as lab training and attend departmental research and academic forums to keep abreast of current trends and practices
- Support development of central stock inventory and establishment of central store with the In Charge of this activity including ordering and follow-up
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